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Archives of Disease in Childhood 1976;51:301-304; doi:10.1136/adc.51.4.301
Copyright © 1976 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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Cystic fibrosis screening in the newborn.

P G Robinson, R B Elliot

A new technique of measuring stool enzyme activity on dry specimens of faeces from newborn children at 4-5 days of age has detected 3 cases of cystic fibrosis in the first 6000 tests. No known cases of cystic fibrosis have been missed. Additionally, one case of pancreatic achylia of at least 4 months' duration has been detected. It is proposed that the detection of cystic fibrosis by this technique is sufficiently practical to be acceptable as a worthwhile newborn screening programme. The screening test has been in use in Auckland for over a year and is now being set up in Hamilton, Wellington, and Dunedin (New Zealand), and Sydney (Australia).








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