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Archives of Disease in Childhood 1989;64:1504-1505
Copyright © 1989 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health
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Archives of Disease in Childhood, Vol 64, 1504-1505, Copyright © 1989 by Archives of Disease in Childhood.

PAPERS

Paracetamol suppositories: a comparative study

S Cullen, D Kenny, OC Ward and K Sabra
Children's Research Centre, Our Lady's Hospital for Sick Children, Dublin.

Paracetamol suppositories in two different bases were given to children who had fever after operations. Plasma concentrations and the effect on temperature were compared. There was a significant correlation between peak plasma concentrations and maximum drop in temperature. A lipophilic base produced better results than a hydrophilic base.




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